Mr Soros, who is backing remain activists who want to keep Britain in the European Union said the bloc was in an “existential crisis” and described the UK’s decision to leave as “immensely damaging”.
His comments came in a speech at a summit organised by the European Council on Foreign Relations think tank in Paris.
He said Brexit was an example of “territorial disintegration” which is “an immensely damaging process, harmful to both sides”.
He told the summit: “Most of the damage is felt right now when the European Union is in an existential crisis, but its attention is diverted to negotiating a separation agreement with Britain.
“That’s a lose-lose proposition, but it could be converted into a win-win situation.
“Divorce will be a long process, probably taking more than five years. Five years is an eternity in politics, especially in revolutionary times like the present.”
George Soros revealed a Remain campaign to block Brexit is set to get under
Best for Britain fought for, and helped to win, a meaningful parliamentary vote which includes the option of not leaving at all
But Mr Soros suggested that the UK had not yet conclusively decided whether it wanted to leave the EU.
He said: “Ultimately, it’s up to the British people to decide what they want to do.
“It would be better however if they came to a decision sooner rather than later. That’s the goal of an initiative called the ‘Best for Britain’, which I support.
“Best for Britain fought for, and helped to win, a meaningful parliamentary vote which includes the option of not leaving at all.
“This would be good for Britain but would also render Europe a great service by rescinding Brexit and not creating a hard-to-fill hole in the European budget.
“But the British public must express its support by a convincing margin in order to be taken seriously by Europe.
“That’s what the Best for Britain is aiming for by engaging the electorate. It will publish its manifesto in the next few days.”
George Soros has financially supported the Best for Britain campaign
Mr Soros, 87, has already donated more than £700,000 to Best for Britain, which was set up shortly before last June’s general election to campaign to overturn the 2016 EU referendum.
Brexit cheerleader Jacob Rees-Mogg said he would be happy for there to be another EU referendum — just not for three decades.
Asked on an LBC radio phone-in show today whether he would accept a second referendum if there was a public demand for one, Mr Rees-Mogg, chairman of the European Research Group of anti-EU Tory backbenchers, said: “We had the biggest democratic exercise in our nation’s history — 17.4 million people voted to leave and of course that should be implemented.
Jacob-Rees Mogg said people voted for Brexit so it should be implemented
“If, in 30 years’ time, the UK wants to rejoin, that would be a matter for the electorate then.
“But this result must be respected and it must be implemented, otherwise we would find our democracy held in as much contempt as that in Greece and Italy by the EU.”